Flavanone 4-reductase
| flavanone 4-reductase | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| EC number | 1.1.1.234 | ||||||
| CAS number | 115232-53-6 | ||||||
| Databases | |||||||
| IntEnz | IntEnz view | ||||||
| BRENDA | BRENDA entry | ||||||
| ExPASy | NiceZyme view | ||||||
| KEGG | KEGG entry | ||||||
| MetaCyc | metabolic pathway | ||||||
| PRIAM | profile | ||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||
| Gene Ontology | AmiGO / EGO | ||||||
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In enzymology, a flavanone 4-reductase (EC 1.1.1.234) is an enzyme that catalyzes the chemical reaction
- (2S)-flavan-4-ol + NADP+
(2S)-flavanone + NADPH + H+
Thus, the two substrates of this enzyme are (2S)-flavan-4-ol and NADP+, whereas its 3 products are (2S)-flavanone, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (2S)-flavan-4-ol:NADP+ 4-oxidoreductase. This enzyme participates in flavonoid biosynthesis.
References
- Stich K and Forkmann G (1988). "Biosynthesis of 3-deoxyanthocyanins with flower extracts from Sinningia cardinalis". Phytochemistry 27 (3): 785–789. doi:10.1016/0031-9422(88)84093-7.